A Theory for Allosteric Temperature-Sensitive Transcription Factors
Zhang, Zechen
We propose a theory for temperature-sensitive transcription factors under
the allostery framework. We show that the allostery theory due to excess
vibrational entropy and conformational energy difference can produce a
thermal switch behavior that is experimentally observed in the literature.
The theory paves the way for a complete model of a tunable thermal
bioswitch.
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